Description
Derma Factory Salmon DNA PDRN Serum
The Salmon DNA PDRN Serum is Derma Factory's PDRN 4% Ampoule, a facial ampoule with 40,000 ppm of PDRN (polydeoxyribonucleotide) obtained from salmon DNA. Its formula combines this ingredient with niacinamide, adenosine, 1% panthenol, hydrolyzed wheat protein, and soluble proteoglycan.
It is designed as a booster within a skincare routine aimed at firmness and elasticity. Its light texture allows it to be mixed with other serums or applied alone, in a thin layer, after toner.
Results reported by the brand
According to the brand's 4-week usage tests, the Salmon DNA PDRN Serum showed a 6.71% improvement in elasticity, a 23.76% reduction in wrinkle appearance, a 4.83% increase in lifting effect, and a 5.29% decrease in visible pigmentation. In consumer perception tests, 87% noticed improvement in wrinkles, 88% perceived greater firmness, and 98% reported a feeling of long-lasting hydration. These data come from studies conducted by the manufacturer; interpret them as informational reference, not as an individual guarantee of results.
PDRN has solid evidence in injectable applications and emerging topical research on skin regeneration; its absorption and benefit in over-the-counter ampoule format remain an active area of study. Niacinamide and adenosine, on the other hand, are ingredients with well-established evidence for barrier care and the appearance of fine lines.
How to use
- After toner, apply an adequate amount evenly over the face.
- If combining with another serum, use 1 to 3 drops mixed in the palm of your hand.
- If using alone, apply a thin layer to prevent the product from not absorbing.
- Wait 2–3 minutes before continuing with the next step of your routine.
- Store the container in the refrigerator before and after opening, and use within 6 months of opening.
Due to its high concentration of PDRN, it can form small pills (*pilling*) if applied excessively or before it is fully absorbed. A more intense aroma after storing in heat does not affect its efficacy, according to the brand.
Featured Ingredients
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PDRN 4% (Sodium DNA): derived from salmon DNA, the main ingredient of the formula.
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Niacinamide: ingredient with consolidated evidence for skin barrier care.
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Adenosine: active recognized for the appearance of expression lines.
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Hydrolyzed wheat protein: ingredient included in the formula.
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Soluble proteoglycan and panthenol: supporting components for the feeling of hydration.
Precautions
The Salmon DNA PDRN Serum is for external use only. Perform a patch test before introducing it into your routine, especially if you have a known allergy to fish or its derivatives, as PDRN comes from salmon DNA.
Do not use on broken, irritated, or actively reacting skin. Discontinue use if itching, burning, or persistent irritation occurs and consult a healthcare professional if symptoms continue. A trending ingredient, yes, but with feet on the ground: consistency, refrigeration, and no promises of science fiction labs.
